Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine
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چکیده
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comparison between conventional and alternative technique in extraction of maxillary molars
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Inducing destruction of specific mRNA using small interfering RNA (siRNA) is a powerful tool in analysis of protein function, but its use as a therapeutic modality has been limited by inefficient or impractical delivery systems. We have used siRNA incorporated into the neutral liposome 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) for efficient in vivo siRNA delivery. In nude mice bearin...
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ژورنال
عنوان ژورنال: Molecular Therapy - Nucleic Acids
سال: 2019
ISSN: 2162-2531
DOI: 10.1016/j.omtn.2019.07.014